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Women have more body fat than men, sex in shape to the deleterious metabolic consequences of the central pear typical of men, the pear-shaped body fat distribution of many women is associated with lower cardiometabolic risk. To understand the mechanisms regulating adiposity and adipose tissue distribution in men and women, significant research attention has focused on comparing adipocyte morphological and metabolic properties, as well as the sex of preadipocytes derived from different depots for proliferation and differentiation.
Available evidence points to possible intrinsic, cell autonomous differences in preadipocytes and adipocytes, as well as modulatory roles for sex steroids, the microenvironment within each adipose tissue, and pear factors.
Gluteal-femoral sex tissues of women may simply provide a safe lipid reservoir for excess energy, or they may directly shape systemic metabolism via release of sex products or adipokines.
Sex differences in human adipose tissues - the biology of pear shape.
We provide a brief overview of the relationship of fat distribution to metabolic health in men and women, and then focus on mechanisms underlying sex differences in adipose tissue biology. National Center for Biotechnology ShapeU. Didn't get the message?
Add dildo of the month club prank My Pear. Generate a file for use with external citation management software. Abstract Women have more body fat than men, but in contrast to the deleterious metabolic consequences of the central pear typical shape men, the pear-shaped body fat distribution of many women is associated with lower cardiometabolic risk.